Porphyria Drug List

App v3.1.1 · Data 2025-02-01 · DrugBank v5.1.13 (2025-01-02)

Drug safety search for people diagnosed with porphyria.

This site is dedicated to people with porphyria. The drug safety information provided here comes from the NAPOS databases (see below) and is meant to help you and your physician decide the risk of taking a particular drug.

Safety Rating

S	Very likely to be safe for prolonged use by individuals with an acute porphyria. No precautions needed.
PRS	Probably safe for prolonged use. No precautions needed.
PSU	Possibly unsafe, only use when no safer alternatives are available. Take precautions with vulnerable patients.
PRU	Probably unsafe, prescribe only on strong or urgent cases. Precautions should be taken in all patients.
U	Very likely to be unsafe for prolonged use by individuals with an acute porphyria. Prescribe only on urgent cases. Precautions should be taken in all patients.

Disclaimer

This application provides a mobile and offline interface to the well known NAPOS database for drug safety information related to porphyria and is meant to be a guide for health care professionals. The prescription of drugs to a patient with acute porphyria is entirely at the risk of the physician in charge.

By using this application you agree that I accept no responsibility for any error, difference of opinion, or any adverse consequences arising from or occasioned by the use of information published on this application.

Warning

For best results, search by the generic drug name or the active ingredient. The brand/trade names listed in this app come from various sources that contain inconcistencies, duplications and errors so it is considered far less accurate.

Country Flags

You can toggle brand/trade name country flags with the button in the seach page. You can also seach for a especific country by typing @cc where cc is a 2 letter ISO country code. Hover over the flags below to see the country name and it's @ code or click on one to see it in action.

Online Resources

Acute Porphyria Drug Database · NAPOS (Norway)
American Porphyria Foundation (APF)
Emergency Room Guidelines (APF)
International Porphyria Network (Ipnet)
National Competence Center for Porphyria Diseases (Norway)
United Porphyrias Association (USA)

Compatibility and Installation

This mobile web application has been tested in iOS 6 and on Android 4.2.2; it also works offline. To save it to your device follow these instructions:

iPhone	Using Safari, navigate to porphyriadrugs.com, tap the (box arrow up) icon at the bottom of the screen, then tap Add to Home Screen.
Android	Using Chrome, navigate to porphyriadrugs.com, tap the (3 dots) menu icon in the upper right-hand corner and tap Add to home screen.

About

My name is Nicolas Frias and I have Acute Intermittent Porphyria, two of my three children have AIP and my sister died years ago of complications of an attack because she was given the wrong medication. Since then, I have carried a list of safe and unsafe drugs with me at all times, but now in the era of ubiquitous internet and smartphones, I decided to create this website and application. Although I am not directly affiliated with APF, UPA or NAPOS, I have a good relationship with all of them.

Attribution

–NAPOS: The Drug Database for Acute Porphyria. The Norwegian Porphyria Centre (NAPOS), 2025-02-01.
–DrugBank: Knox C, Wilson M, Klinger CM, et al. DrugBank 6.0: the DrugBank Knowledgebase for 2024. Nucleic Acids Res. 2024 Jan 5;52(D1):D1265-D1275. doi: 10.1093/nar/gkad976. PMID: 37953279; PMCID: PMC10767804.
–National Library of Medicine: This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.
–ChEMBL Web Services: Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1) W612-W620.
jQuery v3.6.3 · tailwindcss.com v3.4.17 · Google Workbox v6.5.4 · flagpedia.net · fontsquirrel.com · glyphter.com · icons.getbootstrap.com

Settings & Privacy

Changes to the options below will take affect next time you reload the web application.

Settings

Strict mode: By unchecking this box the Safety Rating PSU will be merged into into PRU.

Privacy
By using this web app you consent to the storage of information in your browser's local storage that is required for its proper functioning. This web app also uses third-party softwre you can op-out by uncheching the corresponding checkboxes below.

Google Analytics: Provides standard usage metrics collection. See their privacy and security statement here.

Disqus: Provides the user comments section. This is a free service and includes advertising. See their privacy and security statement here.